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2008
Summer Scientific Conference |
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Program Information by Date
Updated June 17, 2008
CFBS 52nd Scientific Conference
6th Northern Lights Summer Conference
June 17 - 20, 2008
University of Manitoba
Fort Garry Campus
Winnipeg, MB
Organized by:
Canadian Federation of Biological Societies
Organisée par la:
Fédération canadienne des sociétés de biologie
Theme:
Biology of Aging - New Answers to
Old Questions
All scientific sessions will be held
in the Engineering Complex
Registration, Exhibits, Poster Sessions, Receptions and Coffee Breaks
will be held a the University Centre, Manitoba Room, Second Floor
Abstracts
Abstract
Index
Speaker's
Abstract Index
CAANCB
Graduate Student Presentations and CFBS Oral Presentations Abstracts
Poster
Presentation Abstracts
Symposium
Speakers and Plenary Lectures Abstracts
The Canadian Federation of Biological Societies
invites you to attend the Sixth Northern Lights Summer Conference
(52nd CFBS Annual Meeting), June 17 - 20, 2008, University of Manitoba,
Fort Garry Campus, Winnipeg, MB.
TUESDAY, June 17, 2008 |
REGISTRATION & INFORMATION
DESKS
1:00 - 4:30 PM
University Centre 2nd Floor
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All scientific sessions will be held in
the Engineering Complex
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| WEDNESDAY,
June 18, 2008 |
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REGISTRATION & INFORMATION DESKS
8:00 - 4:30 PM
University Centre 2nd Floor
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All scientific sessions will be held in the Engineering Complex |
| 8:30
- 10:00 AM
E2-350
Sponsored by: Canadian Association
for Anatomy, Neurobiology and Cell Biology
CAANCB Graduate Students Presentations
8:30AM
Jiequn Weng, and Jiming Kong,
Department of Human Anatomy and Cell Sciences, University of Manitoba.
Neocrostatin-1 Protects Hypoxia Induced Neuronal Death by
Inhibiting BNIP3.
8:45AM
Rubin Jiao(1), J. Ronald Doucette(2)
and Adil J. Nazarali(1), (1)College of Pharmacy and Nutrition, and
(2)Department of Anatomy and Cell Biology, College of Medicine.
University of Saskatchewan. Effects of Aging on Myelin Ogligodendrocyte
Gylcoprotein and Olig2 Expression in the Rostral Corpus Callosum
of Mice.
9:00AM
H. Ratia, J. Salame, J.A. Thliveris,
M. Xu and J.E. Scott, Departments of Oral Biology and Anatomy, Faculties
of Dentistry & Medicine, University of Manitoba, Winnipeg, and
the Biology of Breathing group, Manitoba Institute of Child Health,
Winnipeg, MB. Insulin-Like Growth Factor Type-I ß
Subunit Receptor Expression in Cigarette Smoke Extract Exposed Fetal
Rat Lung.
9:15AM
Aleksandra Glogowska, Thomas
Klonisch, Department of. Human Anatomy and Cell Science, Faculty
of Medicine, University of Manitoba. Proepidermal Growth
Factor Cytoplasmic Domain and Proteasomal Degradation: a Novel Way
to Regulate Growth in Human Thyroid Carcinoma.
9:30AM
Qi Zhang, Eisenstat, Department
of Human Anatomy and Cell Science Faculty of Medicine, University
of Manitoba. Identification and Characterization of BRN3B
as Dlx Homeobox Gene Transcriptional Targets in Retinal Development.
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| 10:00 - 10:30 AM
Coffee Break
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10:30 - 11:30 AM
E2-350
Sponsored by: Canadian Association for Anatomy, Neurobiology
and Cell Biology (CAANCB)
Murray L. Barr
Award Lecture
Gene Environment Interactions in Type 2 Diabetes: of Carboxypeptidases,
Calcium and Calpains.
Dr. James D. Johnson, Department
of Cellular & Physiological Sciences, University of British Columbia,
Vancouver, BC.
About the Murray L. Barr Award
The Murray L. Barr Award is presented annually to an outstanding
young scientist in recognition of special merit and achievement
in the field of anatomy, neurobiology or cell biology. Dr. Johnson
is indeed a worthy recipient of this award. Congratulations.
Mini-Biography
Dr. James D. Johnson is an Assistant Professor in the Department
of Cellular and Physiological Sciences at the University of British
Columbia. His post-doctoral work, which he completed at Washington
University, was supported by fellowships from CIHR, JDRF and NSERC.
He is a Michael Smith Foundation for Health Research Scholar &
CIHR Senior Fellow/CIHR New Principal Investigator. His research
is well funded by the Michael Smith Foundation for Health Research,
the Juvenile Diabetes Research Foundation, the Canadian Diabetes
Association, the CFI and the CIHR.
His research interests include:
- Molecular and cellular physiology of the human and genetically
engineered pancreatic ß-cells and its relationship to the
pathophysiology and treatment of diabetes.
- Signal transduction mediation apoptosis, gene expression, secretion
and hormone synthesis in endocrine cells by hormones and growth
factors
- Physiological functions of established and novel intracellular
calcium stores, with emphasis on the specificity and spatio-temporal
coding of intracellular signals
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11:30 - 12:00 PM
University Centre - Manitoba Room
Opening
Cermonies
Guest of Honour: Dr. Emoke J.E. Szathmáry, President
of the University of Manitoba
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| 12:00
- 2:00 PM
University Centre - Manitoba Room
Exhibits
Reception, Posters & Exhibits
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2:00 - 3:00 PM
E3-270
Sponsored by: CIHR - Institute of Aging
The Future is
Aging:
CIHR-Institute of Aging - Research Dialogue
The goal of this session is to
expand the dialogue between Canadian bio-scientists and the CIHR
Institute of Aging. Dr. Anne Martin-Matthews, Scientific Director
of the Institute of Aging will open the hour with an overview
of the strategic directions of the Institute including opportunities
for funding in support of research, capacity-building, workshops,,
and other knowledge translation and exchange activities. Participants
will then be invited to discuss with the Institute and members
of its Advisory Board, ideas for enhancing basic and multidisciplinary
research on aging in Canada, and offer suggestion on how the Institute
might better engage this research community.
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3:00 - 4:00 PM
E3-270
Plenary Lecture
Aging is No Longer an Unsolved Problem
in Biology.
Leonard Hayflick, University
of California, San Francisco, USA
Mini-Biography
Dr. Leonard Hayflick is Professor of Anatomy at the University
of California, San Francisco. In 1968 Dr. Hayflick was appointed
Professor of Medical Microbiology at the Stanford University
School of Medicine and in 1982 he moved to the University of
Florida, where he became Director of the Center for Gerontological
Studies, Professor of Zoology and Professor of Microbiology
and Immunology in the College of Medicine.
He is a member of many professional societies
and is a past President of the Gerontological Society of America.
He is a founding member of the Council of the National Institute
on Aging, NIH and Chairman of its' Executive Committee. He was
a consultant to the National Cancer Institute, the World Health
Organization and was Editorial-in-Chief of “Experimental
Gerontology” for thirteen years. Dr. Hayflick is best
known for his breakthrough research in cell biology, virus vaccine
development and mycoplasmology. He overturned a sixty year old
dogma by showing that cultured normal human and animal cells
have a limited capacity to replicate and that only cancer cells
are immortal. This former is known today as “The Hayflick
Limit.” This discovery revealed the mortal cell to be
the location of fundamental age changes and that immortality
was a property of cancer cells. The molecular basis for the
Hayflick Limit is now known to be telomere attrition and the
immortality of cancer cells to depend on the expression of telomerase.
Dr. Hayflick’s work in virus vaccine
research revolutionized the way human vaccines are produced.
He developed the first normal human diploid cell strain (WI-38)
that became widely used for aging research. He showed that WI-38
was also the safest substrate for the production of human virus
vaccines and made the first licensed oral polio vaccine on a
continuously propagated cell strain. WI-38, or copies of it,
have been used to safely immunize almost one billion people
against such virus diseases as poliomyelitis, rubella, rubeola,
varicella, mumps, measles, rabies, adenoviruses and hepatitis
A. Dr. Hayflick is also well known for his discovery of the
cause of primary atypical pneumonia (“Walking Pneumonia”).
He discovered that the etiological agent is a mycoplasma,- the
smallest free living microorganism and named the agent, Mycoplasma
pneumoniae. Dr. Hayflick is also the author of the popular book
“How and Why We Age”, published in 1994 in nine
countries.
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4:00 - 4:30 PM
Coffee Break
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4:30 - 6:30 PM
E3-262
Sponsored by: Danone Institute Canada
SYMPOSIUM 1:
Nutrition as a Determinant of Successful Aging.
Co-Chairs:
Peter Jones, University of Manitoba, Winnipeg, MB
Stephen Cunnane, University of Sherbrooke, Sherbrooke, QC
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4:30 PM
Food Group Consumption of Elderly Community-Dwelling Canadian
Men and their Perceptions of Diet, Health and Life Satisfaction.
The Manitoba Follow-up Study.
Christina O. Lengyel, University of Manitoba, Winnepeg,
MB
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5:00 PM
What are Elderly Canadians Eating?
Katherine Gray-Donald PhD, McGill University, Montreal,
QC
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5:30 PM
Nutrition and Frailty. What do we know? The NuAge Longitudinal
Study
Hélène Payette, Université
de Sherbrooke, Sherebrooke, QC
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6:00 PM
Fish, Omega-3 Fatty Acids and Brain Health During Aging: How
Good is the Evidence?
Stephen Cunnane, University of Sherbrooke,
Sherbrooke, QC.
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4:30 - 6:30 PM
E3-270
Sponsored by: CIHR - Institute of Aging
SYMPOSIUM 2:
Muscles: from Molecules to Mobility.
Chair: Judy Anderson, University of Manitoba, Winnipeg,
MB
- 4:30 PM
The Impact of Stretch, Exercise, and Drug Treatments on Structure,
Function and Stem Cell Activation in Aging Skeletal Muscle
Jeff Leiter, University of Manitoba, Winnipeg, MB and
PanAm clinic
- 5:00 PM
Skeletal Muscle Flexibility: From Basic Science to Practical Application
Jason Peeler, University of Winnipeg, Winnipeg, MB
- 5:30 PM
What Influences Head Motion During Gait? Changes in Motor Control
Following Low-Velocity Whiplash Perturbations
Michael Pierrynowski, Mc Master University, Hamilton,
ON
- 6:00 PM
Mobility Among Older Adults: The Role of Personal and Environmental
Factors
Verena Menec, Centre on Aging, University Manitoba, Winnipeg,
MB
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6:45 - 8:30 PM
University Centre - Manitoba Room
Danone Institute
Wine & Cheese Reception |
| THURSDAY,
June 19, 2008 |
REGISTRATION & INFORMATION
DESKS
8:00 - 4:30 PM
University Centre 2nd Floor
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All scientific sessions will be held in the Engineering Complex |
8:30 - 11:30 AM
E3-270
SYMPOSIUM 3:
Calpain: A Molecular Monkey Wrench Involved in Aging
and Cell Death Mechanisms
Chair: James Gilchrist, University of Manitoba, Winnipeg,
MB
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8:30 AM
Strategies for inhibiting calpains
Peter L. Davies, Queen's University, Kingston, ON
- 9:00 AM
Survival and death functions of calpain
Peter A. Greer, Queen's Cancer Research Institute, Kingston,
ON
- 9:30 - 10:00 AM Coffee Break
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10:00 AM
The Role of Calpains verses Caspase-3 in different Forms of
Neuronal Cell Injury
Kevin K.W. Wang, Banyan Biomarkers, Inc., Alachua,
FL, USA
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10:30 AM
Calpain mediated pathway of death in Parkinson's disease
David S. Park, Neuroscience East - Ottawa Health
Research Institute (OHRI), Ottawa, ON
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11:00 - 11:30 AM
Open Discussion Period
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8:30 - 11:30 AM
E3-262
SYMPOSIUM 4:
Cardiovascular System and Aging: Exercise Blood Flow
Chair: Don Paterson, Canadian Centre for Activity
and Aging, School of Kinesiology, University of Western Ontario,
London, ON
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8:30 AM
Exercise Training Reverses Age-Related Endothelial Dysfunction
in the Skeletal Muscle Resistance Vasculature: Role of NO and
Oxidant Stress
Judy M. Delp, Center for Interdisciplinary Research
in Cardiovascular Sciences, West Virginia University School
of Medicine, USA
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9:00 AM
Tipping the Balance: Pro and Antioxidant Influences on Skeletal
Muscle Hyperemia in the Elderly
D. Walter Wray, Department of Medicine, Physiology
Division University of California at San Diego (La Jolla) and
Department of Medicine, Division of Geriatrics, University of
Utah, USA
- 9:30 - 10:00 AM Coffee Break
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10:00 AM
Dynamics of Microcirculatory Function and Oxygen Delivery in
Aged Muscle
David C. Poole, Departments of Kinesiology, Anatomy
and Physiology, Kansas State University
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10:30 AM
Blood Flow to Contracting Muscles of the Aging Human: Adaptive
or Maladaptive?
David N. Proctor, Associate Professor of Kinesiology,
Physiology and Medicine, Noll Laboratory, The Pennsylvania State
University, USA
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11:00 - 11:30 AM Open
Discussion Period
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| 11:45 AM
- 12:30 PM
E3-270
Sponsored by: CIHR - Institute of
Aging
Plenary Lecture
Making the Political and Scientific Case for Aging Research
Huber Warner, University of Minnesota, St. Paul,
Minnesota, USA
Mini-Biography
Dr. Warner received a Ph.D. in Biochemistry from the University
of Michigan and he later worked as part of the Department of Biochemistry
at the University of Minnesota. His research interests included
virus replication and mechanisms of DNA repair. He is a fellow of
the Gerontology Society of America, in addition to being the editor-in-chief
of the Journal of Gerontology, Biological Sciences. Dr. Warner was
also a part of the National Institute of Aging, where he managed
the Molecular Biology program. His particular interests in lieu
with aging include oxidative stress, mechanisms of apoptosis, functional
genomics and cell replacement mechanisms.
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12:30 - 3:00 PM
University Centre - Manitoba Room
CFBS Reception,
Posters & Exhibits
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| 1:30 - 3:00 PM
University Centre - Beausejour Room
CFBS
Board Meeting and Information Session |
3:00 - 6:00 PM
E3-270
Sponsored by: CIHR - Institute of Aging
SYMPOSIUM 5:
Neuromuscular Function and Resistance training in
Older Adults -From Laboratory Research to Clinical Implications
Chair : Michelle Porter, University of Manitoba,
Winnipeg, MB
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3:00 - 6:00 PM
E3-262
SYMPOSIUM 6:
The AAA Alarm: Antioxidants, Atherosclerosis and Aging
Chair: Mohammed Moghadasian, University of Manitoba,
Winnipeg, MB
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6:45 - 7:00PM
Forty Garry Campus University Club/Pembina Hall
CAANCB Annual General
Meeting
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7:00 - 9:00 PM
Fort Garry Campus University Club, Pembina Hall
Department of Anatomy
Reception: CAANCB members and students
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| FRIDAY,
June 20, 2008 |
REGISTRATION & INFORMATION
DESKS
8:00 - 4:30 PM
University Centre 2nd Floor
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All scientific sessions will be held in the Engineering Complex
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| 8:30 - 11:30
AM
E3-270
SYMPOSIUM 7:
Dilemmas of Drug Therapy in the Elderly
Co- Chairs: Dan Sitar, University of Manitoba, Winnipeg,
MB and Dr. Ruby Grymonpre
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8:30 - 11:30
AM
E3-262
SYMPOSIUM 8:
Biology of Alzheimer and Dementia
Chair: Gordon Glazner, University of Manitoba, Winnipeg,
MB
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8:30 - 11:30
AM
E2-350
Sponsored by: CIHR - Institute of
Aging
SYMPOSIUM 9:
The Role of Oxidative Stress in the Decline of Aged
Muscle
Chair: Russ Hepple, University of Calgary, Calgary,
AB
- 8:30 AM
Role of Oxidative Stress on Potential Mechanisms of Age-Related
Skeletal Muscle Atrophy
Holly Van Remmen, South Texas Veterans Health Care
Administation, San Antonio, Texas, USA
- 9:00 AM
Age-Related Muscle Dysfunction: The Role of Protein Modifications
LaDora Thompson, University of Minnesota, Minneapolis,
MN, USA
- 9:30 - 10:00 AM Coffee Break
- 10:00 AM
Impact of Aging on Skeletal Muscle Mitochondrial Function
and the Role of Oxidative Stress
Russ Hepple, University of Calgary, Calgary, AB
- 10:30 AM
Mitochondrial Iron Accumulation with Age: Consequences for Mitochondrial
Function
Christiaan Leeuwenburgh, University of Florida, FL.,
USA
- 11:00 - 11:30 AM
Open Discussion Period
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11:30 AM - 1:00 PM
E3-262
Sponsored by: Canadian Society
of Exercise Physiology
Symposium X
Physical Activity Guidelines for Canadian
Older Adults
Chair: Mark Tremblay, Children's
Hospital of Eastern Ontario Research Institute, Ottawa, ON
- 11:30 AM
Physical Activity Measurement and Guidelines Project - An
Overview
Mark Tremblay, Children's Hospital of Eastern Ontario
Research Institute, Ottawa, ON
- 11:50 AM
Aging, Physical Activity and Health: Cardiorespiratory Factors
Donald Paterson, University of Western Ontario,
London, ON
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12:20 PM
Aging, Physical Activity and Health: Muscular and Other
Factors
Gareth Jones, School of Occupational Therapy,
Elborn College, London, ON
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12:50 PM
Panel Q+A / Discussion
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1:00 - 2:00 PM
University Centre - Manitoba Room
Goodbye Lunch
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2:00 - 4:00 PM
Pony Corral Restaurant
CIHR Café
Scientifique : Sarcopenia– Muscle Loss that is Associated
with Aging
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Michelle M.Porter (Café Facilitator),
University of Manitoba, Winnipeg, MA
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Russell Hepple, University
of Calgary, Calgary, AB
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Phil Chillibeck, University
Saskatchewan, Saskatoon, SK
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Roger E. Fielding, Tufts University,
Medford, MA
Members of the public are encouraged
to attend. Registration required by June 6, 08. Please send your
registration for this event to Dr. Michelle Porter portermm@ms.umanitoba.ca
Appetizers will be provided. Come and join us!
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2:00 - 5:00 PM
E2-350
Measuring Physical
Activity: A Hands-on Workshop
Dean Kriellaars
This workshop will familiarize the participant
with various physical activity measurement techniques and provide
the neuromuscular and mechanical foundations of these techniques.
Mechanical and electronic pedometry, accelerometry, heart rate,
and GPS will be addressed. Case examples will be provided with each
participant supplied with raw and processed data files. Technique
comparisons will be highlighted with benefits and limitations illustrated.
Demonstrations of the equipment and associated techniques will be
provided. Signal processing and data analysis and reduction methods
will be shown.
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2:00
- 5:00 PM
CFBS Oral
Presentations
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Session #1
E3-270
Chair: Elizabeth Ready,
University of Manitoba, Winnipeg, MB.
2:00PM
Aleksandra Glogowska(1),
Ekkehard Weber(2), Cuong-Vu(3), Thomas Klonisch(1), (1)Department
of Human Anatomy and Cell Science, Faculty of Medicine, University
of Manitoba, (2)Department Physiological Chemistry, (3)Clinics of
Surgery, Martin Luther University, Halle, Germany. Epidermal
Growth Factor Cytoplasmic Domain is a Major Functional Compponent
of the Membrane Anchoring Region of PROEGF and a Novel Regulator
of Elastin Invasiveness of Human Thyroid Carcinoma Cells.
2:25PM
Yali Xie, Sabine
Mai, Jiuyong Xie, Robert P. Shiu, Department of Physiology, Manitoba
Institute of Cell Biology, University of Manitoba. Identifying
Molecular Targets of Oxidative DNA Damage.
2:50PM
Daniel Marsh,
Melanie Wilcox, Ahmed Ghaly, Department of Anatomy and Neurobiology,
Dalhousie University. TGFb - Mediated Fibrosis Predominates
Following Muscle Contusion in Old Rats.
3:45PM
Ender Terzioglu,
M. Mehtap, M. Munnuver and R. Gorczynski, Akdeniz University and
Reo Health Inc, Antalya Turkey and University Health Network.
Age-Related Changes in Monocyte and Lymphocyte Cytokine Production
and their Modulation Following Aerobic Exercise.
4:10PM
Xinbo Li*, and James I Nagy*,
Department of Physiology, University of Manitoba. Interaction
fo Connexin36 with Multi-PDZ-Domain Protein 1, Zonula Occludens-2
and Zonula Occludents-3.
4:35PM
Xiaowei Song, Ryan D'Arcy, John
Fisk, Sultan Darvesh, Steven Beyea, Kenneth Rockwood National Research
Council Canada, Institute for Biodiagnostics - Atlantic & Division
of Geriatric Medicine, Dalhousie University, Halifax. Imaging
of a Prefrontal Neurocompensatory Effect in Early Alzheimer's Disease.
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Session
#2
E3-262
Chair: Brian MacNeil, University of
Manitoba, Winnipeg, MB.
2:00PM
Vijitha Senanayake,
Ali Banigesh, Lingyun Wu, Paul Lee, Bernhard Juurlink, Departments
of Anatomy & Cell Biology, Pharmacology and Physiology, University
of Saskatchewan. Sulforaphane Lowers Systolic Blood Pressure
and Prevents Renal Vascular Remodelling in SHRSP Rats.
2:25PM
Huda E. Tawfik(1), Mohammad
A. Ali(2), Richard Schulz(2), and Susan K. Kaufman, (1)Departments
of Physiology and (2)Pharmacology, Faculty of Medicine and Dentistry,
University of Alberta. Effect of Parity on Vascular Compliance
and Collagen Content.
2:50PM
Ganghong Tian, Lei Wang, Jixian
Deng, Bo Xiang, Jian Wang, Marco Gruwel, John Rendell, Miriam Glogowski,
Boguslaw Tomanek, Darren Freed, Roxanne Deslauriers, and Rakesh
C. Arora. Institute for Biodiagnostics, NRC. Adipose-Derived
Stem Cells are an Effective Therapy for Heart Failure.
3:45PM
Melanie Plourde*, Tremblay-Mercier
J*, Fortier M*, and Cunnane SC, Research Center on Aging, Department
of Medicine, and Physiology and Biophysics, Université de Sherbrooke.
Omega-3 Supplementation Does Not Increase Ketones in Plasma of Healthy
Young and Elderly Adults.
4:10PM
Troy Harkness, Spike D. Postnikoff,
Mackenzie E. Malo, and Berchman P. Wong. Fkh1p, Fkh2p and
the Anaphase Promoting Complex partner in Controlling Chronological
Lifespan in Saccharomyces cerevisiae. |
5:00 - 6:00 PM
E3-262
Sponsored by: Canadian Association for
Anatomy, Neurobiology and Cell Biology (CAANCB)
JCB Grant Award
Lecture
Thirsty Business: Cell, Region and Membrane
Specificity of Aquaporins in the Efferent Ducts and Epididymis
of Rats
Dr. Louis Hermo, Dept. of Anatomy
& Cell Biology McGill University, Montreal, QC
About the Award
The J.C.B. Grant Award is presented annually to an outstanding
scientist in recognition of their merit and achievement in research
and teaching in anatomy, neurobiology or cell biology. Dr. Hermo
is indeed a worthy recipient of this award. Congratulations
Mini-Biography
Dr. Louis Hermo is a Professor at McGill University in the Department
of Anatomy and Cell Biology. His research on the male reproductive
system is well funded by CIHR, NSERC, and TSRI. He has trained
over 30 graduate and post-doctoral fellows in anatomy and cell
biology. Dr. Hermo is highly regarded as not only as a researcher
but also as a teacher. He developed a gross anatomy course for
undergraduate students which has become one of the most popular
and innovative courses on campus. He is also actively teaching
a high subscribed course to 4th year medical students: “Anatomy
for Surgeons.”
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6:00 - 9:30 PM
Manitoba Museum
Sponsored by: Canadian Association for
Anatomy, Neurobiology and Cell Biology (CAANCB)
CAANCB Annual
Quebec Dinner and Award Ceremony
6:00 - 6:45 PM
Light Reception as individuals arrive at the Museum.
6:45 - 7:45 PM
Presentation and Guided Tour from Dr. Graham Young (also a Professor
of Geology at the University of Manitoba)
7:45 - 9:30 PM
Dinner in the Nonsuch Gallery looking out at the two-masted Nonsuch
which sailed to the Hudson's Bay in 1668. Hosted by Inn at the
Forks. Music will be provided by students from the University
of Manitoba Faculty of Music.
Regular Member Rate: $40
Student Rate: $20
Tickets are available at Registration Desk Tuesday
noon, all day Wednesday & Thursday morning.
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