Wednesday, June 14, 2006
Biology Room 106
8:00– 8:30 AM

Brief Welcome
Chaired by Dr. Michael Ratcliffe, CFBS President

PLENARY LECTURE:


• Three-Dimensional Presentation of Data
  Christoph Sensen, University of Calgary, Calgary, AB

Wednesday, June 14, 2006
Biology 106
9:30 AM - 12:30 PM

Symposium 1:

Analytical Micro-Imaging

Chair: Susan Kaminskyj, University of Saskatchewan

• 9:30 - 10:00 AM
  Transmission electron microscopy and 3D reconstruction of microtubule arrays in Aspergillus hyphae
  Robert Roberson, Arizona State University, USA
  
  
• 10:00 - 10:30 AM
  3D Reconstruction of the Mu Transposase and the Type 1 Transpososome by Scanning Transmission Electron Microscopy and Electron Spectroscopic Imaging
  George Chaconas, University of Calgary, Calgary, AB
  
  
• 10:30 - 11:00 AM Coffee break Geology Atrium
  
  
• 11:00 - 11:30 AM
  Synchrotron-Based Soft X-Ray Spectromicroscopy of Biofilms
  Adam Hitchcock, McMaster University, Hamilton, ON
  
  
• 11:30 AM - 12:00 PM
  Exploring Microbial Cells by Atomic Force Microscopy.
  Yves Dufrene, Catholic University of Louvain, Belgium
  
  
• 12:00 - 12:30 PM
  Vitamin E Imaging and Localization in the Neuronal Membrane.
  Eric Monroe, University of Illinois, USA

Geology Atrium
12:30 – 1:00 PM

• Lunch

Wednesday, June 14, 2006
Room: Biology 106
1:00- 2:00 PM

Sponsored by: Canadian Association of Anatomy Neurobiology Cell Biology (CAANCB)

Murray L. Barr Award Lecture
Kurt Haas, Faculty of Medicine, Vancouver, BC

Wednesday , June 14, 2006
Synchrotron Building
2:00 - 3:00 PM

Tour of Canadian Light Sources

Symposium 2:

Multi-Photon Microscopy

Chair: Wolfgang Walz, University of Saskatchewan, Saskatoon, SK

• Introduction: Applications of Multi-Photon Microscopy in Cell Physiology
  Wolfgang Walz, University of Saskatchewan, Saskatoon, SK
  
  
• 2:00 - 2:30 PM
  In Vivo Imaging of Neurons and Microglia with Two-Photon Microscopy
  Wen-Biao Gan, New York University, USA
  
  
• 2:30 - 3:00 PM
  Photorelease of Caged Compounds with Two-Photon Laser Light
  Sean Mulligan, Brain Research Centre, University of British Columbia, Vancouver, BC
  
  
• 3:00 - 3:30 PM Coffee Break
  
  
• 3:30 - 4:00 PM
  Use of Semiconductor Quantum Dots
  Dardo Ferrara, Emory University, Atlanta, USA
  
  
• 4:00 - 4:30 PM
  Second Harmonic Generation Imaging of Normal and Diseased Tissue
  Paul Campagnola, University of Connecticut, Farmington, USA
  
  
• 4:30 - 5:00 PM
  Imaging Protein Interactions in Single Cells with Förster Resonance Energy Transfer and Fluorescence Lifetime Imaging
  Steven S. Vogel, National Institutes of Health, Rockville MD

Wednesday, June 14, 2006
8:30 - 9:30 PM
A315 Health Sciences Building

CAANCB EXECUTIVE AND ANNUAL GENERAL MEETING

Wednesday, June 14, 2006
8:30 - 11:00 PM
Louis Pub

CAANCB Graduate Student Mixer

Come join us for fun and drinks.

Thursday, June 15, 2006
Room: Biology 106
1:00 - 2:30 PM

CAANCB Graduate Students Presentations

Chair: Dr. Hugo Bergen, Department of Human Anatomy & Cell Science, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba

• 1:00 – 1:13 PM
  Abs 25 - Minqi Xu, Dept. of Oral Biology, University of Manitoba. Nicotine Induces Apoptosis-Associated Molecular Modifications in HL-60 Leukemia Cells.
  
  
• 1:13 – 1:26 PM
  Abs 04 - Sara T. Rigley MacDonald, Dept. of Anatomy & Cell Biology, University of Saskatchewan. Amino Acid Supplementation After Spinal Cord Injury Greatly Increases Functional Recovery and Tissue Sparing in a Dose-Dependant and Injury Severity-Dependant Manner.
  
  
• 1:26 – 1:39 PM
  Abs 35 - Xia Wang, College of Pharmacy and Nutrition, University of Saskatchewan. Analysis of Hoxa2 Gene Expression in the Developing Mouse Palate After Exposure to Hoxa2 Sense or Antisense Retrovirus.
  
  
• 1:39 – 1:52 PM
  Abs 28 - Mohammed Allouh, Dept. of Anatomy & Cell Biology, University of Saskatchewan. Expression Patterns of Myod and Myogenin in Satellite Cells and Myonuclei During Development of Skeletal Muscle.
  
  
• 1:52 – 2:05 PM
  Abs 34 - Arianna Servili, Department of Biology, Wilfrid Laurier University, Waterloo, ON. and Dept. of Biology, University of Cádiz, Spain. Establishment of Neuroendocrine Cell Lines from Sea Bass Dicentrarchus Labrax.
  
  
• 2:05 – 2:18 PM
  Abs 22 - Kyla Huebner, Dept. of Human Anatomy & Cell Science, University of Manitoba, Combating Fibrosis in Mdx Mice with a Novel Antifibrotic Drug – Halofuginone.
  
  
• 2:18 – 2:31 PM
  Abs 19 - Akela Hanson, Dept. of Anatomy & Cell Biology, University of Saskatchewan. The Role Of Iron in Neurodegeneration in Drosophila.

Thursday, June 15, 2006
Synchrotron Building
2:00- 3:00 PM

Tour of Canadian Light Sources

SYMPOSIUM 3: (PM Session)

Synchrotron Approaches to Cancer Research

Chair: Elisabeth Schültke and Robert Griebel, University of Saskatchewan, Saskatoon, SK

• 2:30 - 3:00 PM
  Brain tumour invasion: cell movement paradigms in two and three dimensions
  Tamra Werbowetski, McMaster Stem Cell and Cancer Research Institute, Hamilton, ON
  
  
• 3:00 - 3:30 PM
  Imaging tumor cells in an animal model of malignant brain tumor
  Christopher Hall , Daresbury Laboratory, U.K
  
  
• 3:30 - 4:00 PM
  Coffee break Geology Atrium
  
  
• 4:00 - 4:30 PM
  High Z Compounds for Synchrotron Stereotactic Radiotherapy, Developments and Perspectives
  Francois Esteve, INSERM-ESRF, Grenoble, France
  
  
• 4:30 - 5:00 PM
  Microbeam Radiation Therapy (MRT) and Tissue Responses
  Jean Laissue, University of Bern, Switzerland
  
  
• 5:00 - 5:30 PM
  The Potential of the Biomedical Imaging and Therapy Beamline (BMIT)
  Dean Chapman, University of Saskatchewan, Saskatoon, SK
  

CAANCB Quebec Dinner 50th Anniversary Celebration

***Bus leaves for CAANCB Annual Quebec Dinner Banquet at 7:00 PM from Place Riel***

Synchrotron Protein Crystallography

Chair: Pawel Grochulski, Canadian Light Source, Saskatoon, SK

• 8:30 AM
  Opening Remarks and Introduction to CMCF (Pawel Grochulski, CLS)
  
  
• 8:40 - 9:20 AM
  Automated structure determination with PHENIX
  Paul Adams, Advanced Light Source, Lawrence Berkeley National Laboratory, California, USA
  
  
• 9:20 - 10:00 AM
  Structural Characterization of E. coli Histidine Synthesis Pathway
  Mirek Cygler, Biotechnology Research Institute, National Research Council of Canada, Montreal, QC
  
  
• 10:00 - 10:30 AM
  Coffee Break Geology Atrium
  
  
• 10:30 - 11:10 AM
  GM/CA Canted Undulator Beamlines for Macromolecular Crystallography: Design and Performance
  Robert Fischetti, Advanced Photon Source, Argonne National Laboratory, Chicago, IL, USA
  
  
• 11:10 - 11:50 AM
  Structural Genomics combines genomic data and structural biology to advance protein fold and function space
  Andrzej Joachimiak, Advanced Photon Source, Argonne National Laboratory, Chicago, IL, USA
  
  
• 11:50 AM - 12:20 PM
  The Structural Biology Center beamlines at the Advanced Photon Source
  Andrzej Joachimiak, Advanced Photon Source, Argonne National Laboratory, Chicago, IL, USA
  
  
• 12:30 - 2:00 PM
  CFBS & CLS Reception Geology Atrium
  
  
• 1:40 - 2:20 PM
  Novel insight from crystallographic studies on an archaeal RadA recombinase
  Yu Luo, Department of Biochemistry, University of Saskatchewan, Saskatoon, SK
  
  
• 2:20 - 3:00 PM
  Structural basis for the autoinhibition and activation of c-Abl tyrosine kinase
  Bhushan Nagar, Department of Biochemistry, McGill University, Montreal, QC
  
  
• 3:00 - 3:30 PM
  Coffee Break Geology Atrium
  
• 3:30 - 4:10 PM
  Assembled Structure of the Mre11/Rad50/DNA complex from X-ray Solution Scattering and Crystallography
  Scott Williams, Department of Chemistry, Scripps College, Claremont, CA, USA
  
  
• 4:10 - 4:50 PM
  Cryotrapping of reaction intermediates - structural exploration of catalysis
  Jurgen Sygusch, Department of Biochemistry, Université de Montréal, Montreal, QC
  

Further details

Molecular Form and Function: Probing Intact Tissues Using Synchrotron Light

Chair: Ingrid Pickering, Helen Nichol, Graham George , University of Saskatchewan, Saskatoon, SK

• 8:30 AM
  Opening Remarks
  
  
• 8:35 - 9:15 AM
  Mammalian metal metabolism mapped with X-ray absorption spectroscopy
  Graham George, Department of Geological Sciences, University of Saskatchewan, Saskatoon, SK
  
  
• 9:15 - 9:55 AM
  Intimations of a new vanadium redox enzymology in whole blood cells of Ascidians
  Patrick Frank, Stanford Synchrotron Radiation Laboratory, California, USA
  
  
• 9:55 - 10:25 AM
  Coffee Break Geology Atrium
  
  
• 10:25 - 11:05 AM
  Imaging tissue with synchrotron IR microspectroscopy: from misfolded proteins to scar tissue and fungi
  Kathleen Gough, Department of Chemistry, University of Manitoba, Winnipeg, MB
  
  
• 11:05 - 11:45 AM
  X-ray absorption spectroscopy as a probe for metals in neurodegenerative disease
  Helen Nichol, Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK
  
  
• 11:45 AM - 12:25 PM
  Soft-x-ray spectromicroscopy of pristine tissues: biominerals, prions and cancer therapies
  P.U.P.A. Gilbert, Dept. of Physics & Synchrotron Radiation Center, U. Wisconsin-Madison, Wisconsin, USA
  
  
• 12:25 - 1:35 PM
  CFBS & CLS Reception Geology Atrium
  
• 1:35 - 2:15 PM
  Environment: Tracing toxic metals in organisms using X-ray absorption spectroscopy and imaging
  Ingrid Pickering, Department of Geological Sciences, University of Saskatchewan, Saskatoon, SK
  
  
• 2:15 - 2:55 PM
  Following sulfur biochemistry in bacteria, plants and animals with X-ray absorption spectroscopy
  Roger Prince, ExxonMobil Biomedical Sciences Inc., New Jersey, USA
  
  
• 2:55 - 3:25 PM
  Coffee Break Geology Atrium
  
  
• 3:25 - 4:05 PM
  X-ray Scatter Imaging – Imaging from Nanometers to Centimeters
  Dean Chapman, Department of Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK
  
  
• 4:05 - 5:00 PM
  “Ask The Expert” Session
  

This Workshop ends with an “Ask The Expert” segment. This open forum will give participants the opportunity to ask the speakers if or how synchrotron light could be used to help answer their particular scientific questions.

Further details

New Instrumentation for Soft X-ray Photon-In-Photon-Out Spectroscopy

Chair: Alex Moewes, University of Saskatchewan, Saskatoon, SK

• 8:30 AM
  Opening Remarks
  

• 8:35 - 9:20 AM
  X-ray Emission Spectroscopy at the Advanced Light Source
  Jonathan Denlinger, Advanced Light Source, Lawrence Berkeley National Laboratory, California, USA
  
  
• 9:20 - 10:10 AM
  Electronic excitations in strongly correlated systems studied with high resolution RIXS
  Giacomo Ghiringhelli, Department of Physics, Politecnico di Milano, Italy
  
  
• 10:10 - 10:30 AM
  Coffee Break Geology Atrium
  
  
• 10:30 - 11:20 AM
  Resonant elastic soft X-ray scattering: a new probe of electronic order in condensed matter systems
  David Hawthorn, Advanced Materials and Process Engineering Laboratory, University of British Columbia, Vancouver, BC
  
  
• 11:20 AM - 12:10 PM
  Synchrotron radiation excited optical luminescence in the energy and time domain: recent developments and prospects
  T.K. Sham, Department of Chemistry, University of Western Ontario, London, ON
  
  
• 12:30 - 2:00 PM
  CFBS & CLS Reception Geology Atrium

Further details

Friday, June 16, 2006
Room: Arts 217
8:30 AM - 12:30 PM

SYMPOSIUM 7:

Research Opportunities in Terahertz (THz) Science and Technology

Chair: Tim May, Canadian Light Source Inc, Saskatoon, SK

• 8:30 AM
  Opening Remarks (Dominique Appadoo, Canadian Light Source Inc.)
  
  
• 8:40 - 9:20 AM
  Terahertz Spectroscopy at the ALS: Examples, Coherence and the Future
  Michael Martin, Advanced Light Source, Lawrence Berkeley National Laboratory, California, USA
  
  
• 9:20 - 10:00 AM
  Studies of Electron Dynamics using THz Sources at the NSLS
  G. Larry Carr, National Synchrotron Light Source, Brookhaven National Laboratory, NY, USA
  
  
• 10:00 - 10:30 AM
  Coffee Break Geology Atrium
  
  
• 10:30 - 11:00 AM
  Applications of high resolution Terahertz spectroscopy
  Robert McKellar, NRC-Steacie Institute of Molecular Sciences, Ottawa, ON
  
  
• 11:00 - 11:30 AM
  Scientific experiments at BESSY using coherent synchrotron radiation in the Far IR
  Ulli Schade, BESSY Synchrotron, Berlin, Germany
  
  
• 11:30 - 12:00 PM
  Backward Wave Oscillators for Terahertz Spectroscopy of Weakly Bound Complexes
  Wolfgang Jaeger, Department of Chemistry, University of Alberta, Edmonton, AB
  
  
• 12:30 - 2:00 PM
  CFBS & CLS Reception Geology Atrium
  

Further details

Friday, June 16, 2006
Room: Arts 146
1:10 - 5:30 PM

SYMPOSIUM 8:

Synchrotron and Advanced Analytical Techniques in the Forensic Sciences

Chair: Tom Kotzer, Canadian Light Source Inc., Saskatoon, SK

• 1:10 PM
  Opening Remarks (Tom Kotzer, Canadian Light Source Inc.)
  
  
• 1:15 - 2:00 PM
  Synchrotron Infrared Spectromicroscopy for Forensics: Spectral Fingerprints from Latent Fingerprints and More
  Michael Martin, Advanced Light Source, Lawrence Berkeley National Laboratory, California, USA
  
  
• 2:00 - 2:40 PM
  New Technologies and the Forensic Identification of Human Remains
  Ernest Walker, Department of Archaeology, University of Saskatchewan, Saskatoon, SK
  
  
• 2:40 - 3:10 PM
  Nuclear Forensics in Canada: Current Activities and Challenges
  Chunsheng Li, Health Canada, Ottawa, ON
  
  
• 3:10 - 3:30 PM
  Coffee Break Geology Atrium
  
• 3:30 - 4:15 PM
  Forensic Applications of Synchrotron and Related Techniques at The Ian Wark Research Institute
  Bill Skinner, Materials and Environmental Surface Science, Ian Wark Research Institute, Mawson Lake, SA, Australia
  
  
• 4:15 - 5:00 PM
  Forensic Science in Support of Environmental and Toxicological Investigations
  Detlef Birkholz, Research and Development, Advanced Light Source Laboratory Group, California, USA
  
  
• 5:00 - 5:30 PM
  Age-at-Death Estimation from Cortical Bone Microstructure: New Insights from 3D Micro-CT Imaging
  David Cooper, Division of Orthopedic Engineering Research, University of British Columbia, Vancouver, BC
  
  

Further details

CLS Activities:

• Canadian Light Source Annual Users’ Meeting
  
  Consult CLS Main Meeting page for details.

CLS Activities:

• Beamline Team Meetings